We use Debian GNU Linux, which is slim, secure, offers a wealth of choices to select software from and is stable in the long term.
Wherever possible, we use software with low ressource consumption and high security standards, even if it is exotic and/or has to be installed by hand.
We avoid Perl and Python wherever possible. We script with the Bourne shell, but avoid bashism’s and bash for executing them. Oh, and we love Tcl and Jimsh.
With Perl and Python we install only the most basic software from Debian, the rest is installed via CPAN and PIP.